In organic chemistry, propyl is a three-carbon alkyl substituent with chemical formula −CH₂CH₂CH₃ for the linear form. This substituent form is obtained by removing one hydrogen atom attached to the terminal carbon of propane. A propyl substituent is often represented in organic chemistry with the symbol Pr (not to be confused with the element praseodymium).

An isomeric form of propyl is obtained by moving the point of attachment from a terminal carbon atom to the central carbon atom, named 1-methylethyl or isopropyl. To maintain four substituents on each carbon atom, one hydrogen atom has to be moved from the middle carbon atom to the carbon atom which served as attachment point in the n-propyl variant, written as −CH(CH₃)₂.

Linear propyl is sometimes termed normal and hence written with a prefix n- (i.e., n-propyl), as the absence of the prefix n- does not indicate which attachment point is chosen, i.e. absence of prefix does not automatically exclude the possibility of it being the branched version (i.e. i-propyl or isopropyl). In addition, there is a third, cyclic, form called cyclopropyl, or c-propyl. It is not isomeric with the other two forms, having a different chemical formula (−C₃H₅ vs −C₃H₇), not just a different connectivity of the atoms.